Cellular models can also be validated on request.

Human cells

CellsDescriptionModel validated by PCBIS for the following services
A549Lung carcinomaCytotoxicity
Caco-2Colorectal adenocarcinoma

Cytotoxicity
Permeability
Integrity of the intestinal barrier

HaCatKeratinocyteCell migration
HEK 293

Kidney embryonic cell

Cytotoxicity
HeLaUterus adenocarcinomaCytotoxicity
HepG2Liver carcinomaCytotoxicity
HL-60Acute promyelocytic leukemiaCytotoxicity
HMC-1Mast cellHistamine assay
HMEC-1Dermal microvascular endothelial cellAngiogenesis
MCF-7Mammary gland adenocarcinomaCytotoxicity
MDA-MB-231Breast adenocarcinomaCytotoxicity
MIAPACA2Pancreas carcinomaCytotoxicity
PANC1 Pancreas epithelioid carcinomaCytotoxicity
PBMCMononuclear cell

Cytotoxicity
Cytokine secretion assay

U-937Histiocytic lymphomaCytotoxicity

Mouse cells

CellsDescriptionModel validated by PCBIS for the following services
RAW 264.7MacrophageCytotoxicity
Nitrite secretion assay