ADME-Tox department

The drug search process is long and tedious. It requires numerous studies and a reworking of the molecules under development. Evaluation of the properties of ADME-Tox (Absorption, Distribution, Metabolism, Excretion and Toxicity) should be conducted during the exploration, optimization and preclinical development phases. These properties make it possible to characterize, sort compounds and predict their behavior after administration in humans.

The service is aimed at academic and non-academic laboratories (companies, start-ups and private companies). The analyzes fall into 3 categories: physicochemistry, in vitro and in vivo.

We work closely with our clients throughout the study process. In addition, all the tests offered by this service are adaptable to customer demand.

We are committed to preserving the confidentiality and intellectual property of the data. The samples provided by the customers remain their exclusive property, they are destroyed after acceptance of the results. Raw data and reports are kept for at least one year.

Equipment

  • QTOF LCMS 9030 (Shimadzu)
  • Triple quadrupole mass spectrometry 8030 (Shimadzu)
  • UHPLC-UV Nexera (Shimadzu)
  • HPLC-UV (Gilson)